By replacing the defective gene associated with Dravet syndrome in mice, scientists successfully alleviated symptoms without ...

Post-mortem examination of a mouse heart shows a clear delineation in blue where TREE gene enhancer sensed and responded to tissue damage of a heart attack. photo - Ken Poss Lab, Duke University ...

Although these non-coding regions do not encode proteins, they contain regulatory elements such as enhancer sequences, which play crucial roles in controlling gene expression. Enhancers can ...

Researchers used powerful technology to analyse thousands of individual cells at once, considering which genes are active.

In a groundbreaking advancement for families grappling with the challenges of Dravet syndrome, a rare and life-altering form ...

which allows for greater flexibility in the control of gene expression. As previously mentioned, enhancer sequences are DNA sequences that are bound by an activator protein, and they can be ...

Some of these “enhancers” regulatory sequences function similarly to the dimmer switches that control the lighting in the living room. In fact, when and where a specific gene is needed ...

An international collaboration of researchers led by Masahito Yoshihara at Chiba University (Japan) has identified novel transcriptional enhancers that regulate gene expression in neuronal development ...

RNA polymerase binds to a region just before the gene, called the promoter, before moving down the DNA to the gene. Enhancers are regions of DNA that act as molecular switches for turning genes on or ...

Enhancers can also work independently of one another to direct composite patterns of gene expression when linked within a common region on the same DNA strand. Upon carrying out their study ...