Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...

DNA polymerase beta (Pol β) is the primary enzyme responsible for processing 1-nt gaps in chromatin during DNA repair. Here, the authors determine the kinetic and structural basis of gap-filling ...

The small study in patients with a rare disorder that causes liver and lung damage showed the potential for precisely targeted infusions. By Gina Kolata Researchers have corrected a disease ...

Scientists found that rapidly evolving DNA regions, known as human accelerated regions (HARs), help human neurons form complex networks, contributing to higher brain function but possibly increasing ...

The effect on the worms was due to something that was being inherited and accumulated in the offspring, yet had nothing to do with any nucleic acid (DNA or RNA) or anything related to them, ...

A research team has identified NEAT1, a long non-coding RNA, as a key player in DNA repair. This discovery links RNA metabolism to genome stability and opens up potential new cancer treatments. Credit ...

The prosecution’s most important piece of evidence is a DNA sample taken from a knife sheath left at the crime scene. Investigators then used investigative genetic genealogy, or IGG, a forensic ...

Contact hotspots are enriched for nucleosome-encoded signals. De novo calling of DNA contacts between molecules is difficult to achieve with microscopy but can be done using capture of chromosome ...

So you saw a fun GIF on X, formerly known as Twitter. That's cool, good for you, seems like fun. Now you want to save it for your own personal use. That's cool, too, but unfortunately a bit more ...

Here we introduce a process called Improved Single-cell Genome Amplification (iSGA), in which the whole single-cell sequencing cycle is completed in a high-efficient and high-coverage manner, through ...

Errors during transcription may play an important role in determining cellular phenotypes: the RNA polymerase error rate is >4 orders of magnitude higher than that of ...