manilatimes3d
Sixty Degrees Pharmaceuticals to Ensure Continuity of Tafenoquine Supply in U.S. by Importing Limited Quantity of KODATEF®
KODATEF is not approved for use in the U.S. Demand for ARAKODA has been steadily growing in recent months as awareness and ...
Agios Pharmaceuticals: Liver Toxicity Issues May Threaten Thalassemia Approval (Rating Downgrade)
Despite promising Phase 3 results, safety concerns, namely liver injury, have impacted Agios stock and could affect Pyrukund's approval and market adoption. Read the full report here.
Agios’ Phase 3 ACTIVATE-Kids Study of Mitapivat in Children with Pyruvate Kinase (PK) Deficiency Not Regularly Transfused Met Primary Endpoint
ACTIVATE-Kids is the First Study to Demonstrate Efficacy of an Oral Therapy for Children with PK Deficiency Who Are Not Regularly Transfused –– ...
Targeted Oncology1d
Participants Discuss Need for Biomarkers in Frontline Metastatic RCC
During a Case-Based Roundtable® event, Neeraj Agarwal, MD, and participants discussed how they might determine which ...
Medscape1d
Immunological Complications of Blood Transfusion
Biochemical tests may reveal hemoglobinemia, elevated lactic dehydrogenase ... can be differentiated from autoimmune hemolytic anemia by the absence of anti-IgG reactivity in the DAT and a ...
The EMBO Journal4d
A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine
A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...
Tempo3d
Free Health Check Program: List of Available Screenings
To access the free health screening, people only need to register through the SATUSEHAT Mobile (SSM) application. Following ...
eLife3d
Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...
Medscape2d
Red Blood Cell Indices: Implications for Practice
Anemia Deficiency in the concentration of erythrocytes and/or hemoglobin concentration; further defined as a hematocrit or hemoglobin greater than 2 standard deviations below the mean for age and ...