Genetic switches could play a role in creating complex eukaryotic genetic circuits for programmed cell-free systems or artificial cells.

Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA ...

Transgenic animals continue to play an essential role in many aspects of zebrafish research, including the development of disease models. The most widely used system for zebrafish transgenesis is the ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

Once a strain was found that lacked a modified base, the gene responsible was identified by complementation with plasmids containing single genes within the deleted region, or by constructing ...

A screen of human-infecting viruses identified extensive examples of viral proteins that resembled human sequences, which could trigger autoimmune diseases like multiple sclerosis.