eLife26d
Rab10 inactivation promotes AMPAR trafficking and spine enlargement during long-term potentiation
This is an important study that describes the development of optical biosensors for various Rab GTPases and explores the contributions of Rab10 and Rab4 to structural and functional plasticity at ...
Frontiers4y
The Small GTPase Rab5c Exerts Bi-Function in Singapore Grouper Iridovirus Infections and Cellular Responses in the Grouper, Epinephelus coioides
Rab5 effectors, such as early-endosome antigen 1 (EEA1) and rabankyrin-5, bind not to Rab5-GDP, but to Rab5-GTP; thus a key determinant of Rab5 function is the duration of the GTP-bound state (3–5).
eLife4y
RETRACTED: Arginine methylation of SHANK2 by PRMT7 promotes human breast cancer metastasis through activating endosomal FAK signalling
Further, SHANK2 R240 methylation reinforced breast cancer cell migration through activating endosome FAK signalling. Collectively, these findings represent one mechanistic explanation for how PRMT7 ...