Specifically, replacing a CH2 group in oxetanes (or a C=O in β-lactones) with a CF2 unit produces α,α-difluoro-oxetanes. These α,α-difluoro-oxetanes uniquely combine the advantages of small ...
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Synthesis method unlocks a pathway to valuable fluorinated drug compounds for new medicinesIn this vein, isosteric replacement of a CH 2 unit within an oxetane (or C=O group within a β-lactone) with CF 2 results in α,α-difluoro-oxetanes, a prized class of heterocyclic compounds with ...
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