Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

Transmission and distribution utilities in Brazil address increasing telecommunications demands to ensure an efficient, ...

enhances GPS/GNSS positioning accuracy by providing real-time differential corrections from its global network ... today presents on its novel SKY-0515 small molecule RNA splicing modulator targeting ...

Methods Whole genome mRNA profiling was performed on lung tissue samples (n=1197) and differential gene expression with increasing ... mammalian target of rapamycin signalling, splicing of introns and ...

Across the hemisphere and beyond, we are witness to the accelerated collapse and evisceration of political institutions and ...

Smith+Nephew (LSE:SN, NYSE:SNN), the global medical technology company, today announces it will showcase the latest advancements in Sports Medicine for joint repair at the American Academy of ...

Dr. Yagi said, “BTB’s focus on novel non-opioid therapies and novel RNA splicing modifiers resonates with our investment thesis to bring innovative therapeutics in the areas of significant ...

My lab is interested in identifying and analysing regulators of the JAK/STAT pathway– a signaling cascade frequently misactivated in haematopoietic malignancies. We use both high throughput RNAi ...

In silico tools for splicing defect prediction have a key role to assess the impact of variants of uncertain significance. Our aim was to evaluate the performance of a set of commonly used splicing in ...