CRISPR system variant shows a novel DNA cleavage mechanism
Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...
Water molecules help proteins read the human genome, research reveals
In a study published in Nature Structural and Molecular Biology, scientists from the Department of Medical Biochemistry and ...
Mouse model unveils dynamics through which SYNGAP1 gene supports cognitive function
The SYNGAP1 gene, which supports the production of a protein called SynGAP (Synaptic Ras GTPase-Activating Protein), is known to play a key role in supporting the development of synapses and neural ...
Gene 'silencer' in junk DNA prevents fatal neurological disease
A team led by University of Pittsburgh School of Public Health geneticists has shown, for the first time, that a gene ...