Heidelberg biochemists and structural biologists from Shanghai unravel the roles of two key regulatory factors in mRNA ...
Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...
They succeeded once they were able to isolate the splicing complexes of the fungus that were in the midst of quality control ...
Our method, depicted in Figure 1e, involves two main components: A transformer-based splicing prediction model (TrASPr) and a Bayesian Optimization algorithm (BOS) to design RNA with desired ...
Synthesis of an RBM39 Degrader That Downregulates CEP192 and Induces Disorganized Spindle Structures
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Rd., Shanghai 201203, China State Key Laboratory of Drug Research, Shanghai ...
With the long-term goal of creating living cells from non-living components, scientists in the field of synthetic biology work with RNA origami. This tool uses the multifunctionality of the ...
Scientists also studied core temperature-response mechanisms, but many crucial components remained unknown ... It actively participates in the spliceosome, a complex that processes RNA before it ...
After, double strand is separated by helicases and create the mature miRNA; on the contrary, in non-canonical pathways, miRNA located within of mirtrons and are associated with spliceosome-dependent ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback