Confocal fluorescence microscopy (CFM) is widely used to make high-resolution cellular images but requires fluorescent staining, which poses risks of photobleaching or phototoxicity, potentially ...

AI transforms label-free photoacoustic microscopy into confocal microscopy Date: January 17, 2025 Source: Pohang University of Science & Technology (POSTECH) Summary: In life sciences, confocal ...

Purpose: To assess the anticancer effect of microbubbles (MBs) in combination with sinoporphyrin sodium (DVDMS)-mediated sonodynamic therapy (SDT) for the in vitro and in vivo treatment of ...

By integrating confocal scanning with structural illumination super-resolution, this approach allows researchers to achieve superior imaging capabilities essential for studying living tissues.

Figure 1. The CellXpress.ai cell culture system components and functionality. Image Credit: Molecular Devices UK Ltd Automation of 3D spheroid/tumoroid assay Figure 2. Schematic diagram of ...

Reference Pellacani G, Fernetani F, Ciardo S, et al. Effect of reflectance confocal microscopy for suspect lesions on diagnostic accuracy in melanoma: a randomized clinical trial. JAMA Dermatol.

In brief, Calcein-AM and PI were added to the samples and incubated in the dark for 15 min at 4°C. The fluorescent images were observed and photographed by a confocal laser scanning microscope (CLSM, ...

Figure 1. Amyloid-β protein fragment 1–42 (Aβ) treatment upregulation of Aβ1-42 and reduces neuronal viability. (A) The expression of AD marker Aβ1-42 detected by Western blot analysis (B) Cell ...

Confocal laser speckle autocorrelation imaging of dynamic flow in microvasculature. Opto-Electron Adv 5, 210045 (2022) . doi: 10.29026/oea.2022.210045 ...

OSW-1 showed slightly lower activity (Kapp = 0.31 μM –1; r50 = 0.78), and the soyasaponin was the lowest in the membrane affinity and the calcein leakage activity (Kapp = 0.017 μM –1; r50 = 1.66). The ...

Resolution: Spatial resolution of a confocal Raman microscope is determined by the numerical aperture of the objective and the excitation wavelength – i.e. the smaller the aperture, the higher the ...

While confocal microscopy has been praised for its high contrast, recent methods show super-resolution microscopy, via the SIM technique, is capable of catching reflectance imaging with more than ...