Focusing on yeast, there are ∼ 20,000 molecules of Pol II in cells of S. cerevisiae 5.Of these, ∼ 60% are hyperphosphorylated on the C-terminal domain and associated with chromatin in a salt ...

Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results from a combination of higher Pol II turnover and lower transcription ...

The Pre-Initiation Complex (PIC), which consists of Mediator, TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA polymerase II (pol II), governs the expression of all protein-coding and most non-coding ...