GSK's marketing application for linerixibat, targeting cholestatic pruritus in PBC patients, gains EMA acceptance based on phase III success.

EMA accepts GSK’s MAA for linerixibat for cholestatic pruritus in patients with primary biliary cholangitis: London, UK Tuesday, June 24, 2025, 09:00 Hrs [IST] GSK plc announced ...

The EMA has started a review of GSK's treatment candidate for primary biliary cholangitis (PBC), linerixibat, offering hope ...

GSK said on Monday that the European Medicines Agency has accepted its marketing authorisation application for linerixibat, an investigational treatment for cholestatic pruritus in patients with ...

Introduction Biliary colic (BC) is a severe pain associated with nausea and vomiting, which is the most common symptom among the gallstone population. This protocol proposes a methodology for ...

(Alliance News) - GSK PLC on Monday said linerixibat has been accepted for review by the European Medicines Agency for the treatment of intense itching caused by a rare autoimmune liver disease.

“If your itching is caused by a liver problem, there won’t be a skin rash or an insect bite,” the Liver Foundation says. The ...

Published (DOI: 10.1136/wjps-2025-001026) on May 12, 2025, in World Journal of Pediatric Surgery, researchers from Geneva University Hospitals conducted the first scoping review of BA screening ...

Lisa Woodcock's initial instinct when she first developed severe itching all over her body was to blame an allergic reaction to her laundry detergent. 'I was itching all the time,' recalls the 41-year ...

Linerixibat improves pruritus and pruritus-associated sleep disturbances rapidly and significantly in patients with primary biliary cholangitis (PBC), according to a new study published in the Journal ...

The FDA has accepted for review the NDA for linerixibat for the treatment of cholestatic pruritus in patients with primary biliary cholangitis.

Pruritus typically starts on the palms of the hands and soles of the feet and is more intense in these areas but can also be widespread. Although a rash specific to ICP is not observed (a rash may be ...