Carboxylic acids are ubiquitous in bioactive organic molecules and readily available chemical building blocks. Carboxylic ...

The development of prodrugs — chemically modified versions of pharmacologically active agents that must undergo transformationin vivoto release the active drug — is a well-established strategy ...

The solubility equilibriums of formic, acetic, levulinic, stearic and naphthenic acids in oil-paper (Kraft) insulation systems have been studied using titration techniques. Temperatures and moisture ...

Two decades of intensive research efforts have led to the discovery of a large number of HIV-1 integrase (IN) inhibitors. Recently, the United States Food and Drug Administration (US FDA) approved ...

Redox transformation of an α,β-unsaturated aldehyde to a carboxylic acid derivative by means of a combination of TMSCN and DBU was investigated. In addition to the wide use of the carboxylic acid ...