This new article publication from Acta Pharmaceutica Sinica B, discusses how SRSF7 promotes pulmonary fibrosis through regulating PKM alternative splicing in lung fibroblasts.

In this study, an up-regulation of serine/arginine-rich splicing factor 7 (SRSF7) was identified in lung fibroblasts derived from IPF patients and a bleomycin (BLM)-induced mouse model, and further ...

Sudemycin K, a derivative that replaces the pharmacophore’s oxycarbonyl by an amide group, displays improved potency as an inhibitor of cancer cell proliferation, as a regulator of alternative ...