The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions ...
Cells have a natural editing system that allows them to rearrange genetic instructions to create different proteins from the ...
“A truncated protein might cause a lot of problems … Nonsense mediated decay is a mechanism to get rid of that RNA before it's translated into a protein.” Alternative splicing plays a pivotal role in ...
A study reveals how cancer disrupts RNA splicing and presents a potential therapy using antisense oligonucleotides to target ...
Scientists from The Jackson Laboratory and UConn Health found that cancer cells disrupt poison exons, leading to tumor growth ...
Scientists reveal how cancer cells manipulate RNA splicing, increasing tumor growth. A new study introduces antisense ...
Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...
Plants survive cold by adjusting at cellular level. Scientists discovered that the PORCUPINE protein helps plants adapt to ...
Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different ...
Researchers have discovered that cancer cells suppress 'poison exons' -- genetic elements that act as an off switch for protein production -- in a key gene called TRA2 , promoting tumor growth.