“A truncated protein might cause a lot of problems … Nonsense mediated decay is a mechanism to get rid of that RNA before it's translated into a protein.” Alternative splicing plays a pivotal role in ...

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In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

Specific RNA Sequences Are Required for Regulation of Alternative Splicing If we want to understand the splice code, then we need to analyze the existing information about constitutive and ...

Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor RNA to produce multiple transcript variants. Alterations in exon exclusion, intron retention ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

In this webinar, Dr. Megan L Noonan will present her research on the role of alternative splicing in kidney disease progression, discussing how she used nanopore RNA sequencing to accurately detect ...

Working at the interface of RNA splicing and breast cancer biology, our current focus is on regulation of breast cancer metastasis driven by alternative splicing. We use molecular biology, genomics, ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

and sites of RNA methylation, to mention a few. It is now clear that regulation of alternative splicing has a huge impact on gene function and there is a great deal to learn about questions ranging ...