We present a one-step, visible light-induced synthesis of bicyclo[1.1.1]pentane-ketone, a bioisostere for benzoyl groups that enhances drug properties. This method operates under mild conditions, ...

Since the 1990s, medicinal chemistry research has demonstrated that replacing benzene rings with bicyclo[1.1.1]pentane derivatives enhances drug ...

School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China University of Chinese Academy of Sciences, ...

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Its mechanism is complicated and involves loss of cells ... enzyme-linked immunosorbent assay, and radical absorbance capacity assay. However, the abundance of some biomarkers is low, requiring more ...

Free radicals are highly reactive and unstable molecules that are made by the body naturally as a byproduct of normal metabolism. Free radicals can also be made by the body after exposure to toxins in ...