The structure of the IRE1α–MKC9989 complex was solved by molecular replacement using CCP4-PHASER 55 and the structure of human IRE1α (PDB 3P23 (ref. 46)) as the search model.

It especially adjusts important chemical reaction in various ways by controlling the conversion of steroid with sex hormone or by converting the fat aldehyde formed during fat reduction4.

The process of generating aldehyde-tagged protein followed by chemical conjugation and purification takes 20 ... B.L. et al. Function and structure of a prokaryotic formylglycine-generating enzyme ...

Determining the structure of a molecule, atom by atom, is important for both chemists and biologists to understand how molecules work and interact with surrounding material.

Light microscopes have revolutionized our understanding of the microcosmos, but their resolution is limited to about 100 nanometers. To see how molecules bond, break, or change their structure, we ...

Scientists have created and imaged the smallest possible five-ringed structure -- about 100,000 times thinner than a human hair. Dubbed 'olympicene', the single molecule was brought to life in a ...

Ethyl methylphenylglycidate is an aromatic organic compound with two functional groups, an ester and an epoxide. It is also known as “strawberry aldehyde” even though it is not found in strawberries ...

American Chemical Society: Chemistry for Life. Traumatic acid, formally trans-2-dodecenedioic acid, is a plant hormone that was isolated from damaged green beans by Caltech chemists James English, Jr.