We present a one-step, visible light-induced synthesis of bicyclo[1.1.1]pentane-ketone, a bioisostere for benzoyl groups that ...

Since the 1990s, medicinal chemistry research has demonstrated that replacing benzene rings with bicyclo[1.1.1]pentane derivatives enhances drug ...

Aldehydes and ketones in the mixture are converted into water-soluble hydrazone derivatives by treatment with the ‘Girard P’ or ‘T’ reagent, and the non-carbonyl compounds are removed by ...

In my previous article, I discussed the mechanism of action of reproxalap: It is a RASP (reactive aldehyde species ... option or similar derivative position in any of the companies mentioned ...

Straightforward skeletal editing chemistry now enables the direct insertion of nitrogen into carbon–carbon double bonds.

The regulator also proposed that derivatives on indices other than the benchmarks BSE Sensex and NSE Nifty 50 only be offered if the index meets certain criteria. India's markets regulator has ...

According to the latest information released by the Fungicide Resistance Action Committee (FRAC), over 30 fungicide selective targets have been identified and acknowledged in the field of fungicide ...

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.joc.4c02074. Deposition Number 2266271 contains the supplementary ...

In addition to ionic Cu 2+, copper oxide nanoparticles (CuONPs) also induced mitochondrial dysfunction with inhibition of mitochondrial dehydrogenases aldehyde dehydrogenase (ALDH2) and glutamate ...

The innate immune response represents the first-line of defense against invading pathogens. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) have been implicated in various aspects of ...