Transcription and RNA splicing are tightly coupled in eukaryotic cells. Here, authors report the multivalent interaction between U1 snRNP and the transcription elongation complex which may allow ...

Wave's chief executive, Paul Bolno, said the trial data is "a significant milestone […] for the entire oligonucleotide field" and "unlocks and derisks" the company's RNA editing platform.

One type of RNP, hnRNPs (heteronuclear proteins), are important in splicing of mRNA (messenger RNA), polyadenylation, stabilization, localization and translation.

A disparity in UK access to a medicine for Duchenne muscular dystrophy (DMD) has been addressed, after Scotland gave a green light to use of PTC Therapeutics' Translarna for the first time. The ...