Also 10-N-nonyl-acridine orange (NAO) is a cell permeant dye. This probe accumulates into mitochondria and binds to phospholipids and, particularly, to mitochondrial cardiolipin 7.

Figure 1. Comparison of viability counts using either brightfield (trypan blue) or fluorescence (acridine orange / propidium iodide) methods. Image Credit: DeNovix Inc.

Arnold H. Eggerth, The Bactericidal Action of Acridine Dyes and the Adjuvant Effect of Serum, The Journal of Infectious Diseases, Vol. 38, No. 5 (May, 1926), pp. 440-460 ...

Pharmacokinetic Evaluation of N-[2-(Dimethylamino)Ethyl]Acridine-4-Carboxamide in Patients by Positron Emission Tomography Authors : Azeem Saleem , Robert J. Harte , Julian C. Matthews , Safiye Osman ...

Neurizon® Therapeutics Limited (ASX: NUZ & NUZOA) ("Neurizon" or "the Company"), a clinical-stage biotech company dedicated to advancing innovative treatments for neurodegenerative diseases, is ...