This Perspective article examines the interplay between antibody diversification mechanisms and highlights the importance of constant regions in influencing the specificity and functionality of ...

In this free webinar, learn about advancements in cell line development and glycoengineering. Attendees will gain insights into how precise glycan modulation boosts antibody-dependent cell-mediated ...

Harrison's plasma contained the rare antibody Anti-D, also known as Rhesus D antibody, which is used to make the medication given to mothers whose blood is at risk of attacking their fetuses.

The medication triggers the death of the inflammation-driving B-cells via two main mechanisms: antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC).

Antibody-independent cell-mediated cytotoxicity (AICC) was measured in wells containing target and effector cells without the addition of AH or control IgG antibodies. The following formula was used ...

For cell staining, nonspecific antibody binding sites were blocked for 30 min using ... Dogs also offer a key animal model for the translation of immunotherapies. The study of ADCC in rodent syngeneic ...

Longitudinal characteristics of heavy and light chain clonal families.

Thus, both nAb and ADCC antibody functions can be detected using the autologous T/F Env as early as 2.9 months after infection. At Time Point 2 (Figure 1B, 7.5 months), nAb activity against the T/F ...