RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

So the cells are able to "read" the instructions for building proteins stored in these genetic mosaic particles, they are ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

The spliceosome then converts them into mature, functional mRNA. To do this, this large protein-RNA complex, which is located in the cell nucleus, removes non-coding sections (introns) from mRNA ...

Spliceosomes are large and dynamic RNA-protein complexes. The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small nuclear ribonucleoprotein particles (snRNPs, read “snurps”) – ...

We study regulation of gene expression by the minor spliceosome. This parallel pre-mRNA splicing machinery functions during the nuclear RNA processing phase and regulates cellular mRNA levels. We ...

RNA splicing is crucial for gene expression. After DNA is copied into messenger RNA (mRNA), noncoding parts called introns are removed, and the coding parts are spliced together.