In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

So the cells are able to "read" the instructions for building proteins stored in these genetic mosaic particles, they are ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

Spliceosomes are large and dynamic RNA-protein complexes. The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small nuclear ribonucleoprotein particles (snRNPs, read “snurps”) – ...

The spliceosome then converts them into mature, functional mRNA. To do this, this large protein-RNA complex, which is located in the cell nucleus, removes non-coding sections (introns) from mRNA ...

The finding Although small interfering RNAs (siRNAs) are largely explored today for their potential in gene therapy, the phenomenon was first described in plants, which employ siRNAs to disable ...

We study regulation of gene expression by the minor spliceosome. This parallel pre-mRNA splicing machinery functions during the nuclear RNA processing phase and regulates cellular mRNA levels. We ...

So the cells are able to "read" the instructions for building proteins stored in these genetic mosaic particles, they are first copied into precursors of mRNA, or messenger RNA. The spliceosome ...