RNA polymerase is an enzyme that is responsible for copying a DNA sequence into an RNA sequence, duyring the process of transcription. As complex molecule composed of protein subunits, RNA ...

Once transcription is initiated, the DNA double helix unwinds and RNA polymerase reads the template strand, adding nucleotides to the 3′ end of the growing chain (Figure 2b). At a temperature of ...

The cell creates mRNA, a copy of DNA, to assemble proteins ... of ribosomes to mRNA during its transcription by the enzyme RNA polymerase, or RNAP. Their study, which looked at the mechanism ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted upon by an enzyme called RNA polymerase. This is a molecular machine ...

A new method for mapping torsion provides insights into the ways that the genome responds to the torsion generated by RNA polymerase II.

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

For the Liu Lab, necessity is truly the mother of invention. The researchers were examining how the 3D organization of the ...

RNA synthesis, or transcription, is the process by which RNA is produced using DNA as a template. This process is carried out by the enzyme RNA polymerase, which binds to specific promoter regions on ...

DNA polymerase enzymes facilitate this process, ensuring accurate copying of the genetic information. Transcription is the process by which the genetic information in DNA is copied into a ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical ...

Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex (PIC) factors. The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, ...

Enzymes called RNA polymerases transcribe DNA into RNA. RNA is the intermediary that carries ... types of RNA polymerases that can transcribe different types of RNA. RNA polymerase II, shown here, is ...