All About Alternative Splicing Enhancing protein diversity and guiding cellular functions, alternative splicing is a key dimension of genetic regulation.

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA).

This new article publication from Acta Pharmaceutica Sinica B, discusses how SRSF7 promotes pulmonary fibrosis through regulating PKM alternative splicing in lung fibroblasts.

Alternative splicing of eukaryotic transcripts is a mechanism that enables cells to generate vast protein diversity from a limited number of genes. The mechanisms and outcomes of alternative ...

Scientists have written a review to discuss emerging research and evidence of the roles of alternative splicing defects in major neurodegenerative diseases. They also summarize the latest advances ...

Q: What role does alternative splicing play in molecular biology? Alternative splicing greatly expands the diversity of the proteins that can be made from a single gene.

Investigators suggest that further research could help discover potential therapeutic approaches that leverage the alternative splicing-nonsense-mediated decay process.

Discovered in the 1970s, the mechanisms of RNA splicing have been well characterized through numerous studies in eukaryotic and prokaryotic systems. In this article, we describe the mechanisms of ...

Alternative splicing is crucial for eukaryotic gene expression and influences protein function and regulation, with mis-splicing linked to numerous diseases.

Alternative Splicing Goes Mainstream In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative ...

Existing splicing-regulating drugs could be potentially employed for this type of cancer; including therapies for individual splicing events, such as the drug nusinersen that is currently used in ...