What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms. Next, the snRNPs U2 and U4/U6 appear to ...
1 The traditional view posits that spliceosome formation is a stepwise affair, with one snRNP binding to the pre-mRNA first, followed by the others in a temporal order. This model is widely held as ...
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Study reveals plants have mechanism for protein blueprint monitoring that was thought to exist only in animal cells"The U1 snRNP complex has a dual function: as part of the spliceosome, it helps to ensure that relevant gene information is properly spliced together. It also ensures that the transcription ...
SF3B1 is part of the U2 snRNP spliceosome complex—a protein complex necessary for proper gene expression. Cancer cells with partial SF3B1 loss die when SF3B1 is moderately suppressed. Image courtesy ...
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA.
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