Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

Together, these snRNAs and proteins form small nuclear ribonucleoprotein particles (snRNPs), setting the stage for splicing. 1 The traditional view posits that spliceosome formation is a stepwise ...

In this study, the researchers reveal the structure of U11 snRNP—one of the five subunits ... who has been working on pre-mRNA splicing machinery for more than 15 years, first decided to focus ...

In this new study, the researchers reveal the structure of U11 snRNP – one of the five subunits of the ... who has been working on pre-mRNA splicing machinery for more than 15 years, first decided to ...

What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms.

This review highlights significant aspects of snRNP and snoRNP biogenesis that ... which are released following pre-mRNA splicing. Interestingly, in some cases, the host genes do not appear ...

is correctly assembled into mature mRNA. Splicing is a basic requirement for producing proteins that fulfill an organism's ...

In a recent article, he showed that when genes are preferentially positioned near speckles, mRNA splicing is significantly more efficient. 4 “It’s huge for the RNA processing field, because now it ...