Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

Together, these snRNAs and proteins form small nuclear ribonucleoprotein particles (snRNPs), setting the stage for splicing. 1 The traditional view posits that spliceosome formation is a stepwise ...

What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms.

This review highlights significant aspects of snRNP and snoRNP biogenesis that ... which are released following pre-mRNA splicing. Interestingly, in some cases, the host genes do not appear ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

Research into splicing mechanisms and patterns is essential for decerning fundamental biological principles, as well as clarifying the molecular basis of many diseases and developing new therapies. 2 ...