AZoLifeSciences on MSN18h
Understanding the Complex Architecture of the Minor Spliceosome
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
News Medical on MSN2d
New Structural Insights Into the Minor Spliceosome
Researchers have revealed the structure of U11 snRNP – one of the five subunits of the minor spliceosome, which initiates the intron selection process.
Nature1mon
Kick-sTARting HIV-1 transcription elongation by 7SK snRNP deporTATion
The work by D'Orso and Frankel 1 spurs several questions. First, what is the mechanism of the TAR-triggered acquisition of Tat and P-TEFb from 7SK snRNP during Pol II pausing? Given that (i) Tat ...