The heart is an omnivore, consuming fuel constantly and using any substrate available. 8 The high rates of ATP production and turnover are critical in maintaining cardiac contractility to deliver ...

Heart failure (HF) is a syndrome affecting all organ systems. While some organ interactions have been studied intensively in HF (such as the cardiorenal interaction), the endocrine gut has to some ...

Cardiovascular disease is the leading contributor to years lost due to disability or premature death among adults. Current efforts focus on risk prediction and risk factor mitigation‚ which have been ...

WORLD OF EVS EVs are 30- to 1000-nm-sized membranous structures released by cells into the extracellular space (Figure 1). Their membrane, composed of a complex lipid and protein repertoire, ...

BACKGROUND: Upper extremity (UE) motor function impairment is a major poststroke complication whose recovery remains one of the most challenging tasks in neurological rehabilitation. This study ...

Supplementation with omega‐3 (n‐3) fatty acid or dietary fish may protect against atherosclerosis, but the potential mechanisms are unclear. Prior studies found modest triglyceride‐lowering effects ...

The present study used RPT, congenic strains, haplotype analysis, sequencing, and gene expression to establish a small number of genetic variants associated with increased susceptibility of the S rat ...

Provoked anger is associated with an increased risk of cardiovascular disease events. The underlying mechanism linking provoked anger as well as other core negative emotions including anxiety and ...

Non–vitamin K oral anticoagulants (NOACs) are now widely used as alternatives to warfarin for stroke prevention in atrial fibrillation and management of venous thromboembolism. In clinical practice, ...

As early as 1699, Chemineau described a heart composed of 2 auricles but only 1 ventricle.1 The univentricular heart has since fascinated the medical community. Unique in its complexity and scope, the ...

T he global prevalence of heart failure (HF) is estimated at >30 million individuals. Rapidly increasing in incidence and prevalence, HF is thought to have contributed to 1 in 8 deaths in 2017. 1, 2 ...

Atrial fibrillation (AF) is a highly prevalent arrhythmia, with substantial associated morbidity and mortality. There have been significant management advances over the past 2 decades, but the burden ...