This, in turn, drives loss of vascular integrity that causes vascular leakage, which results in a drop in blood pressure (and in severe cases septic shock) and reduced organ perfusion that can ...

Medically reviewed by Jane Kim, MD Early signs of sepsis may include severe pain, shortness of breath, and mental confusion.

It causes millions of deaths each year ... In the Third International Consensus Definitions for Sepsis and Septic Shock (2016), the concepts applicable to sepsis and septic shock were redefined ...