Professor Vlad Pena's group focuses on the structural basis of human pre-mRNA processing under normal, pathological and drug-induced conditions. X. Donate. ... Strand displacement is primarily known ...

The journey from gene to protein is complex and tightly controlled within each cell. It consists of two major steps: transcription and translation. Here, we describe the processes of transcription and ...

This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...

Argonaute family members are effectors in small RNA-mediated silencing. In vitro analysis of the four human Argonautes demonstrates that AGO1 and AGO2 mediate multiple rounds of microRNA strand ...

Splicing is closely linked with transcription, involving a dynamic interaction between the mRNA, RNA polymerase II (Pol II), and chromatin structures. 5 “There's strong evidence that splicing of ...

BOSTON--(BUSINESS WIRE)--Strand Therapeutics, the programmable mRNA company developing curative therapies for cancer and other diseases, announced today preclinical data from its programmable mRNA ...

BOSTON--(BUSINESS WIRE)--Strand Therapeutics, the world’s first programmable mRNA company developing curative therapies for cancer, autoimmune diseases, and beyond, today announced the first ...

Mechanisms and Regulation of pre-mRNA Splicing. Professor Vlad Pena's group focuses on the structural basis of human pre-mRNA processing ... Strand displacement is primarily known from the DNA field, ...