The central dogma of biology defines the flow of genetic information: It describes how proteins are made from mRNA templates, which are in turn made from DNA. Exporting the mRNA from inside the ...

In the fast-evolving field of medical science, a new artificial intelligence model may be about to change the way mRNA-based drugs and vaccines are designed. Developed through a collaboration between ...

Anya Hillery, Ph.D., SLU-Madrid health sciences professor currently on excedencia, publishes "mRNA Therapeutics: Foundations, Innovations and Clinical Applications" with the help of SLU's prestigious ...

The goal of my laboratory is to define the sequence-structure-function relationships that underpin mRNA regulation and non-coding function in cells. We aim to translate our findings into mechanistic ...

The popularity of mRNA-based therapeutics has surged over the past few years. To ensure the safety of these treatments, scientists need to analyze the characteristics of the manufactured molecules, ...

In drug discovery, proteins may be king—they are the target of nearly all small-molecule drugs. But there remains an even larger untapped drug target: RNA. The classic view of RNA is one of a long, ...

The binding of small molecules to distinctive three-dimensional structures in mRNA provides a new dimension in RNA control, previously limited to the targeting of secondary structures with antisense ...

Researchers from the Broad Institute and Massachusetts Institute of Technology (MIT) have engineered multi-tailed mRNAs that boost mRNA activity levels in cells by as much as 20x and last 2-3 times ...

It took a global pandemic, but the critical role of messenger RNA in all of life’s functions has taken center stage in the past year with the successful rollout of mRNA vaccines to combat the SARS-Cov ...

Researchers at Arizona State University’s (ASU) School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution have discovered an unprecedented pathway producing ...