Jamie-Lynn Sigler and Robert Iler, who played siblings Meadow and A.J. Soprano, respectively, face off in PEOPLE's exclusive ...

The Sopranos' actress Jamie-Lynn Sigler, 43, remembers nights when she ‘fell apart, terrified’ fearing her son Beau 'was going to die' after he was diagnosed with acute disseminated encephalomyelitis, ...

Christina Applegate is shedding more light on her battle with multiple sclerosis. “For three years, since I was diagnosed, ...

Christina Applegate and Jamie-Lynn Sigler share painful MS experiences on MesSy podcast, offering support and advice for ...

Christina Applegate is letting fans in on some of the details of her struggle against MS over the past three years.

They’ve done every test known to man on me, put so much radiation into my body from CT scans to everything else,” the “Dead ...

Friends and Anchorman actress Christina Applegate is one of several famous faces to be living with MS, a condition that is ...

Jamie-Lynn Sigler is going up against her Sopranos brother, Robert Iler, on The $100,000 Pyramid! In PEOPLE's exclusive look at the March 23 episode of the game show, the two former costars ...

Jamie-Lynn Sigler is reflecting on the scariest time in her life when her 11-year-old son Beau was hospitalized with a life-threatening autoimmune condition last summer. “Those were the hardest ...

Jamie-Lynn Sigler is going up against her Sopranos brother, Robert Iler, on The $100,000 Pyramid! In PEOPLE's exclusive look at the March 23 episode of the game show, the two former costars prepare to ...

Jamie-Lynn Sigler has learned to live with pain since being diagnosed with multiple sclerosis when she was 20 — but nothing prepared her for the kind of anguish she faced last summer when her 11 ...