Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

DNA polymerase (DNAP) is a type of enzyme that is responsible for forming new copies of DNA, in the form of nucleic acid molecules. Nucleic acids are polymers, which are large molecules made up of ...

Through the technique of DNA sequencing, first developed by Frederick Sanger, scientists can determine the exact order of nucleotides in an organism’s genes. Knowing this order is the first step ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted upon by an enzyme called RNA polymerase. This is a molecular machine which ...

Forensic DNA profiling uses polymerase chain reaction (PCR) to amplify short tandem repeats (STRs), which are highly variable DNA regions, typically with four repeating bases. This variability helps ...

Enzymes called RNA polymerases transcribe DNA into RNA. RNA is the intermediary that carries ... types of RNA polymerases that can transcribe different types of RNA. RNA polymerase II, shown here, is ...

The double helix unwinds, and each strand serves as a template for the synthesis of a new complementary strand. DNA polymerase enzymes facilitate this process, ensuring accurate copying of the genetic ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA clearance following damage, driven by the exonuclease activity of the mtDNA ...

Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex (the large protein and phosphoprotein). Not only that, but they also ...