((Reuters)) - American Sean Brady scored the biggest win of his career with a superb submission over ex-welterweight champion Leon Edwards to silence the crowd at London's O2 Arena and catapult himself into contention for a shot at compatriot Belal Muhammad's title.

Sean Brady took Belal Muhammad's blueprint and one-upped him at UFC Fight Night 255. Brady (18-1 MMA, 8-1 UFC) dominated former welterweight champion Leon Edwards (22-5 MMA, 14-4 UFC) on the ground then submitted him with a guillotine choke in

Sean Brady secures a guillotine choke submission against Leon ... More Edwards of Jamaica in a welterweight fight during the UFC Fight Night even

LONDON – UFC Fight Night 255 takes place Saturday at The O2, and you can watch a live video stream of the post-event news conference here on MMA Junkie. Expected to take part in the press conference are the winners of the main and co-main event matchups of Leon Edwards vs. Sean Brady and Jan Blachowicz vs. Carlos Ulberg.

He was back in London as the division's No. 1 contender this time and faced fifth-ranked Sean Brady atop a UFC Fight Night show at the O2 Arena. Edwards was taken down nine times and controlled for better than 12 minutes in the title loss to Belal Muhammad,