In 2023, after a brief hiatus, tuberculosis regained from COVID its status as the world’s deadliest infectious disease—a ...

Get Instant Summarized Text (Gist) Mycobacterium tuberculosis (Mtb) manipulates host cell death pathways to facilitate infection by promoting necroptosis and inhibiting apoptosis. The Mtb effector ...

Tuberculosis vaccine shows superior immune response protection in nonhuman primates when compared to existing BCG vaccine A ...

The World Health Organization warned last week that the sweeping funding cuts could endanger millions of lives, since many countries depend on foreign aid for TB prevention, testing and treatment.

The team used single-cell RNA sequencing and advanced imaging techniques to compare the immune response between animals ...

Therapeutic vaccines made of detoxified, fragmented Mycobacterium tuberculosis cells (e.g., RUTI) delivered in liposomes were developed to reduce the period of chemotherapy. The rationale of this ...

U.S.A.I.D. Global Health The United States was the major funder of tuberculosis programs. Now hundreds of thousands of sick patients can’t find tests or drugs, and risk spreading the disease.

Tuberculosis remains one of the most lethal infectious diseases caused by a single pathogen. According to the latest global ...

Treatment of TB usually requires several months of antibiotic ... Granulomas are composed of a fibrous capsule which surrounds a layer of immune cells and a core of dead tissue (necrotic core ...

However, how Mtb manipulates host molecular switches of cell death pathways to reprogram cell death modalities and drive tuberculosis pathogenesis remains poorly understood. In a study published ...