During translation, multiple ribosomes travel along the nucleic acid chain to build polypeptides that become functional proteins. Occasionally, these molecular decoders pause on the mRNA, either ...

Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active ...

Scientists say that officials from the National Institutes of Health urged them to remove references to mRNA vaccine ...

Abe's team overcame this hurdle by introducing a cap structure into the circular mRNA itself. This internal cap structure ...

Abe's team overcame this hurdle by introducing a cap structure into the circular mRNA itself. This internal cap structure triggers translation initiation, bypassing the need for IRES sequences ...

Sanofi has been forging ever-closer ties with its mRNA partner Translate Bio since the two started working together in 2018, and has now gone all in, offering $3.2 billion to buy the company outright.

Cancer metastasis, the spread of cancer to organs, is a major cause of cancer-related deaths. Once cancer spreads to multiple ...

Regulation of the poly(A) tail is essential for selective protein translation in early embryos. However, the mechanisms that determine and maintain the length of maternal mRNA poly(A) tails remain ...