Medically reviewed by Steffini Stalos, DO People with sickle cell disease are immunocompromised, which means they have an increased risk of infection. For this reason, immunizations are an important ...

The spleen contains many blood vessels since one of its primary functions is filtering blood. Injury to the spleen can damage these blood vessels and cause significant bleeding that leaks into the ...

Contrary to established dogma, the spleen is not the principal source of the pro-inflammatory cytokine called tumor necrosis factor (TNF), which drives the sort of system-wide inflammation seen in ...

Here, the authors target the spleen to reduce acute heart injury and improve long-term cardiac function via transient IRF7 inhibition. Neudesin is identified as an inhibitor of erythrophagocytosis ...

When the disease affects the splenic artery or vein, the adjacent spleen is often removed. After removal of the end of the pancreas, the remaining portion of the organ functions normally by producing ...