In sickle cell disease, the mutation causes hemoglobin to change shape, distorting red blood cells into stiff "sickle" shapes that block up blood vessels. More efficient editing ...

Beta thalassemia results from mutations in the HBB gene, which gives your body instructions for producing hemoglobin, a protein in red blood cells that carries oxygen. This leads to abnormal ...

Blood transfusions could be a regular thing if you or your child has a blood disorder called beta thalassemia. The disease causes a drop in the amount of red blood cells you have.

The prevalence of thalassemia varies by region, but experts estimate that up to 5% of the world’s population carry a gene for alpha-thalassemia, while about 1.5% carry a gene for beta-thalassemia.

Enzyme identified as possible novel drug target for sickle cell disease, Thalassemia Date: July ... reduces the characteristic sickling that distorts the shape of red blood cells and gives the ...

Beta thalassemia makes your spleen make more new blood cells and break down more old blood cells than usual, so it has to work harder. Just like a muscle grows when you use it more, overuse makes ...

A Northeast Ohio woman and a 22-year-old man from UAE are among the first patients to receive the innovative CRISPR treatment.

Tan, PH, Hwang, WY, Goh, YT, et al. Unrelated peripheral blood and cord blood hematopoietic stem cell transplants for thalassemia major. Am J Hematol 2004;75:209-212 Crossref ...

Blood cells must squeeze through the body's smallest blood vessels, called capillaries, to do their job, but capillaries often become narrower than the cells in their normal disc shape. So the ...

Expert joins CBS New York to discuss new sickle cell treatment 02:46. Britain's medicines regulator has authorized the world's first gene therapy treatment for sickle cell disease, in a move that ...

A gios Pharmaceuticals said Monday that its drug called mitapivat reduced the need for blood transfusions in patients with a severe form of beta-thalassemia, an inherited blood disorder. The ...