Splicing occurs in two distinct steps and requires extensive reorganization of the spliceosome during the process. The complexity of this reaction has kept an army of biochemists busy for the last ...

At least a dozen other steps are needed before the splicing reaction concludes. Not much is known about how the minor spliceosome transitions through these intermediate steps. "This has been a ...

In contrast, exon recognition is thought to occur before the splicing reaction. The main evidence for this is that disruption of an individual splice site most often leads to the entire exon being ...

At least a dozen other steps are needed before the splicing reaction concludes. Not much is known about how the minor spliceosome transitions through these intermediate steps. "This has been a ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns ...

Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global impact on cellular homeostasis and intricate molecular mechanisms remains ...

Different conformations of Tetrahymena ribozyme in the self-splicing reactions. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert!

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts. RNA splicing is a cellular ...