A new study reveals that blocking ribosomal RNA production rewires cancer cell behavior and could help treat genetically ...

Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger RNA—a prerequisite for protein synthesis in the cell. The poorly ...

Disparate fields have provided advances in our understanding of the impact of protein-synthesis errors on cellular fitness, disease and evolution. Although organisms show adaptations to minimize ...

Protein synthesis in nerve cell dendrites underlies long-term memory formation in the brain, among other functions. Knowing how proteins are made to order at the synapse can help researchers ...

Before protein synthesis can proceed, noncoding regions (introns) of mRNA must be removed and the coding regions (exons) joined together. Sign up for C&EN's must-read weekly newsletter Email Address * ...

If pseudo splice sites are used instead of the correct splice sites during protein synthesis, the resulting mRNA will contain the wrong instructions – cryptic splicing – that could alter ...

Alternative splicing enables a single gene to encode multiple mRNA variants and, consequently, diversifies protein isoform products. The advent of deep sequencing technologies has revealed that 95 ...

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs -- single-stranded RNAs involved in protein synthesis -- and proteins from the same stretch of DNA ...

When the genetic code is transcribed into RNA for protein synthesis, alternative splicing can lead to the production of different transcripts from the same gene, depending on the selected genetic ...

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic ...

Because an increase in TFIIIA protein upregulates synthesis of 5S rRNA 23, the discovery of P5SM shows that ribosomal protein L5 can directly control the production of its partner, 5S rRNA.