Shown is the splicing pathway. The pre-messenger RNA (pre-mRNA) has exons (blue) and introns (pink). The spliceosome (not shown) was known to catalyze two chemical reactions (black arrows ...

Blaustein and colleagues concluded that activation of the PI 3-kinase signaling pathway by Ras(V12-C40) in turn activated AKT kinase, resulting in a change in the fibronectin splicing pattern to ...

Plants survive cold by adjusting at cellular level. Scientists discovered that the PORCUPINE protein helps plants adapt to ...

As climate conditions become increasingly unpredictable, understanding how plants respond to cold is crucial for securing ...

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts. RNA splicing is a cellular ...

Defining where to start cutting out the introns is just the first step in the spliceosome's complex assembly pathway. At least a dozen other steps are needed before the splicing reaction concludes.

A human-specific NOVA1 variant changed mouse vocalizations, potentially providing insights into the evolution of language.

This RNA-RNA interaction is important for recognizing and committing the pre-mRNA to the splicing pathway. However, it is not sufficient to determine ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns ...