With the participation of U5, the 3′ end of the intron is brought ... creating new proteins without disrupting the function of the old gene. Our knowledge of RNA splicing is quite new.

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a ...

During splicing, U4/U6.U5 normally ensures the immediate ... types of cancer that are highly dependent on the correct function of the spliceosome." Some highly aggressive tumors produce large ...

Splicing is a basic requirement for producing proteins that fulfill an organism's vital functions. Faulty functioning of a spliceosome can lead to a variety of serious diseases. The genetic ...

Splicing is a basic requirement for producing proteins that fulfill an organism’s vital functions. Faulty functioning of a spliceosome can lead to a variety of serious diseases. Researchers at ...