A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA.

What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms. Next, the snRNPs U2 and U4/U6 appear to ...

How does the cell select this information? A large molecular machine called the spliceosome continuously separates the coding and non-coding regions of our genes—and it's doing this even as you ...

Get Instant Summarized Text (Gist) A new regulatory mechanism in RNA splicing has been identified, involving LUC7 proteins that influence spliceosome targeting of specific 5' splice sites. This ...

Comparative genomics approaches have already shown that the basic mechanistic components that diversify immunoglobulin and T cell antigen receptors ... and spliceosome levels, may demonstrate ...