The Galej Group at EMBL Grenoble has published new structural insights into minor spliceosome function in the journal Molecular Cell.

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing ...

The spliceosome is critical for the proper functioning of every cell, and numerous genetic disorders are linked to problems with spliceosome function. In most eukaryotic cells, two types of ...

Tango Therapeutics rebounds with a stronger pipeline, renewed focus on PRMT5 inhibitors, and key data ahead despite past setbacks. See why TNGX stock is a buy.

Researchers at the Centre for Genomic Regulation (CRG) in Barcelona have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine in human biology ...

Detailed map of the spliceosome is being made publicly available to help researchers pinpoint exactly where splicing errors are occurring in a patient's cells.

It’s been a busy week for a cancer drug target called PRMT5 that may play a role in treating a variety of solid tumors. Amgen on Friday presented preliminary results from its first study of an ...

After a decade of work, scientists have completed a molecular model of the human spliceosome, an incredibly complex cellular machine. When an active gene is expressed in a cell, it is transcribed into ...

The spliceosome and Group II introns are believed to share a common ancestor that was responsible for spreading introns throughout the genome, but while Group II introns can splice themselves out of ...

Tango has last dance with PRMT5 inhibitor, pirouettes into embrace with 2 sibling molecules By Nick Paul Taylor Nov 6, 2024 8:28am Tango Therapeutics solid tumor synthetic lethality clinical trial ...