The spliceosome is critical for the proper functioning of every cell, and numerous genetic disorders are linked to problems with spliceosome function.

Researchers at the Center for Genomic Regulation (CRG) in Barcelona have created the first blueprint of the human spliceosome ...

Spliceosome Structure And Function; ... The spliceosome is a dynamic macromolecular machine responsible for the precise excision of introns from pre-messenger RNA (pre-mRNA), ...

The spliceosome is critical for the proper functioning of every cell, and numerous genetic disorders are linked to problems with spliceosome function.

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome ...

The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small nuclear ribonucleoprotein particles (snRNPs, read "snurps") – and about 150 proteins, involved in different stages ...

Transcriptome-wide splicing network reveals specialized regulatory functions of the core spliceosome. Science , 2024; 386 (6721): 551 DOI: 10.1126/science.adn8105 Cite This Page : ...

The Galej Group at EMBL Grenoble has provided new insights into minor spliceosome function, revealing the structure of U11 snRNP – one of its subunits, ...

The scientists’ work revealed that different components of the spliceosome have unique regulatory functions. “Collectively, our results demonstrate how systematic, ...

Team finds how a key enzyme of the spliceosome exerts its controlling function. by Freie Universitaet BerlinFreie Universitaet Berlin ...

Protein complexes such as the nineteen complex (NTC), nineteen-related (NTR), retention and splicing complex (RES) and other non-snRNP proteins participate in spliceosome assembly and function 23.