This is even more true for molecular machines that are scarce in cells, like the minor spliceosome. "One of the biggest challenges in studying this complex was to figure out how to selectively ...

This is even more true for molecular machines that are scarce in cells, like the minor spliceosome. "One of the biggest challenges in studying this complex was to figure out how to selectively ...

The vast majority of introns are removed by the major spliceosome, a 60 S complex containing five small ... 5' splice site to release the upstream exon and form a branched or lariat splicing ...

when spliceosome components were depleted or inhibited pharmacologically, the steady-state levels of circular RNAs increased while expression of their associated linear mRNAs concomitantly decreased.