This means that a spliceosome discarded during cellular quality control can be represented at the atomic level for the first time. "However, analyzing the components flexibly bound to the ...

The fit between a splice site and the spliceosome components that bind it influences splicing activity. Strong splice sites closely match consensus sequences and are efficiently recognized by the ...

The spliceosome, which forms on introns ... "A lot of what we know about how splicing works and what the core components are actually comes from relatively old yeast genetics work," Kenny says.