The minor spliceosome: Researchers reveal new structural insights into an essential RNA-protein complex
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
AZoLifeSciences on MSN4h
Understanding the Complex Architecture of the Minor Spliceosome
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
The spliceosome: An atomic-level look into how cells avoid errors when manufacturing mRNA
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...
EurekAlert!7d
Spliceosome: How cells avoid errors when manufacturing mRNA
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA.
BioTechniques7y
Hitting cancer where it’s vulnerable
SF3B1 is part of the U2 snRNP spliceosome complex—a protein complex necessary for proper gene expression. Cancer cells with partial SF3B1 loss die when SF3B1 is moderately suppressed. Image courtesy ...
Hosted on MSN2mon
Slow editing of protein blueprints leads to cell death, spliceosome study discovers
During splicing, this transcript undergoes modification: a cellular editing complex, the spliceosome, removes certain segments. The outcome varies depending on which parts are cut out, resulting ...
Nature14d
RNA splicing articles from across Nature Portfolio
For many eukaryotic introns, splicing is done in a series of reactions which are catalyzed by the spliceosome, a complex of small nuclear ribonucleoproteins (snRNPs) and associated proteins ...
How Cells Avoid Errors When Manufacturing mRNA
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...
idw6d
Spliceosome: How Cells Avoid Errors When Manufacturing mRNA
Structural biologists provide a first-time look at the atomic level into the quality control mechanism of this complex molecular machine A complex molecular machine, the spliceosome, ensures that ...